Could PRP for rotator cuff or hip soreness help?

What may ease shoulder or hip soreness?

Shoulder soreness may rise when you reach overhead, lift away from your body, or sleep on that side. Outer-hip soreness may grow after long walks, repeated stairs, or lying on the sore side. You might place often-used items lower and break one long walk into shorter outings. It’s often easier to move gently than to stop for many days. Please seek timely care after a pop, major new weakness, fever, spreading warmth, or a fast increase in night soreness.

We’d rather help you notice those signs early.

What did the PRP studies find?

QC Kinetix uses the term biologic therapies for non-surgical care it makes there with blood from you. One shoulder study gave both groups shots and the same exercise plan, but the PRP group didn’t do better than the group given saline, a simple mix of salt and water. Another study found better short-term pain and use scores with PRP than with a steroid shot. In one outer-hip study, people given PRP reported less soreness and better daily use than those given a steroid shot, with the difference lasting two years.

Those results can guide questions, but they can’t predict your result.

Sources

1. A placebo-controlled, double-blind randomized trial of 40 patients with chronic rotator cuff tendinopathy compared a single ultrasound-guided subacromial injection of 5 mL PRP with 5 mL saline, with both groups completing a 6-week standard exercise programme and follow-up to one year. PRP did not produce better outcomes than saline on any measure - a reminder that the exercise programme, not the injectate, carried the improvement.

   Kesikburun S, Tan AK, Yilmaz B, et al. — Platelet-rich plasma injections in the treatment of chronic rotator cuff tendinopathy: a randomized controlled trial with 1-year follow-up. American Journal of Sports Medicine, 2013. DOI: 10.1177/0363546513496542.

2. A double-blind randomized controlled trial of 99 patients with imaging-proven partial-thickness rotator cuff tears or tendinopathy compared ultrasound-guided PRP with corticosteroid, following patients to 12 months. PRP produced significantly better short-term pain relief and function than corticosteroid on VAS, ASES and WORC scores.

   Kwong CA, Woodmass JM, Gusnowski EM, et al. — Platelet-Rich Plasma in Patients With Partial-Thickness Rotator Cuff Tears or Tendinopathy Leads to Significantly Improved Short-Term Pain Relief and Function Compared With Corticosteroid Injection: A Double-Blind Randomized Controlled Trial. Arthroscopy, 2021. DOI: 10.1016/j.arthro.2020.10.037.

3. A meta-analysis of eight randomized trials of PRP for rotator cuff tendinopathy concluded PRP was a safe and effective intervention for long-term pain control and shoulder function - while noting that the studies varied in PRP preparation and injection technique and that the control interventions differed between trials (saline in four, rehabilitation or dry needling in the other four).

   A Hamid MS, Sazlina SG — Platelet-rich plasma for rotator cuff tendinopathy: A systematic review and meta-analysis. PLOS ONE, 2021. DOI: 10.1371/journal.pone.0251111.

4. A randomized double-blind trial of 80 patients with chronic gluteal tendinopathy (lateral hip pain) compared a single ultrasound-guided PRP injection with a single corticosteroid injection. At 12 weeks the PRP group had significantly better modified Harris Hip Scores (P=.048), and 82% versus 56.7% of patients reached the minimal clinically important difference (P=.016).

   Fitzpatrick J, Bulsara MK, O'Donnell J, et al. — The Effectiveness of Platelet-Rich Plasma Injections in Gluteal Tendinopathy: A Randomized, Double-Blind Controlled Trial Comparing a Single Platelet-Rich Plasma Injection With a Single Corticosteroid Injection. American Journal of Sports Medicine, 2018. DOI: 10.1177/0363546517745525.

5. Two-year follow-up of the same 80-patient gluteal tendinopathy trial found the single leukocyte-RICH PRP injection produced improvement that was sustained at 104 weeks (mHHS 53.77 at baseline to 82.59 at two years; P<.0001), whereas the corticosteroid improvement peaked at six weeks and was not maintained beyond 24 weeks. This is one of the clearest demonstrations that leukocyte-rich PRP is the formulation with evidence in TENDON, not in cartilage.

   Fitzpatrick J, Bulsara MK, O'Donnell J, et al. — Leucocyte-Rich Platelet-Rich Plasma Treatment of Gluteus Medius and Minimus Tendinopathy: A Double-Blind Randomized Controlled Trial With 2-Year Follow-up. American Journal of Sports Medicine, 2019. DOI: 10.1177/0363546519826969.